Specialty-format research
PT-141
Sexual-response signaling through melanocortin receptors: the peptide also known as bremelanotide.
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PT-141 reconstitution calculator
- Labeled vial
- Swabs + syringe
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Research use only
PT-141A melanocortin pathway with a neural focus
A clear starting point. Follow the research, unpack the terminology and compare related profiles.
What is PT-141?
PT-141, or bremelanotide, is a cyclic seven-amino-acid peptide with an unusual history: it is a metabolite of Melanotan II. Researchers noticed that when Melanotan II broke down, one of its by-products acted on the nervous system rather than on pigment cells. That by-product was developed separately into PT-141.
What do researchers investigate?
Central nervous system signalling
Distinction from vascular-acting compounds
Unpack the terminology
Tap a term to see what it means.
Receptor
A protein that recognises a signal. Studying receptor binding helps explain which cellular pathway a molecule may engage.
Agonist
A molecule that activates a receptor. The receptor target and the experimental setting both matter when interpreting a result.
Reading and sources
Search PubMedPut the profiles side by side
Compare research directions and labelled formats. Choose a related material to explore the difference.
PT-141
Sexual-response signaling through melanocortin receptors: the peptide also known as bremelanotide.
Melanotan II
Melanin and pigmentation: a cyclic α-MSH analogue for studying the skin's pigment pathways.
A closer look at the details
What is PT-141?
A cyclic seven-amino-acid peptide, also known as bremelanotide, that acts on melanocortin receptors. Mainly MC4R, in the central nervous system. It is approved in the US under the name Vyleesi. Listed here as a non-clinical research material.
How is PT-141 related to Melanotan II?
PT-141 is a metabolite of Melanotan II. Researchers noticed the breakdown product acted on the nervous system rather than pigment cells, and developed it as a separate compound.
What does the amount on the label mean?
The label records the amount or volume in the vial. It identifies the format; it does not define a use regimen.
Research context, not a promise of clinical effects. Read each study in its original experimental setting.
Available options.
PT-141
What is PT-141?
A cyclic seven-amino-acid peptide, also known as bremelanotide, that acts on melanocortin receptors. Mainly MC4R, in the central nervous system. It is approved in the US under the name Vyleesi. Listed here as a non-clinical research material.
How is PT-141 related to Melanotan II?
PT-141 is a metabolite of Melanotan II. Researchers noticed the breakdown product acted on the nervous system rather than pigment cells, and developed it as a separate compound.
How do I check PT-141 availability?
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